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REDUCING KRATOM TOLERANCE

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REDUCING KRATOM TOLERANCE

Kratom tolerance is the number one impediment when looking to ensure peak medicinal effects. Besides taking this plant less frequently, there are some tricks one can use to keep tolerance low.

STRAIN ROTATION

SUPPLEMENTATION

Strain rotation is a fantastic way to keep the medicinal effects of kratom fresh. When using a specific strain for a long period, you can develop a tolerance to its specific alkaloid profile; however, by switching strains daily, the alkaloid levels do not remain stable enough to develop a full tolerance to the effects. Methods Rotation by Effects – This method involves using alternating strains types (e.g. Mon. – Sedating, Tues. – Stimulating, Weds. – Sedating) Rotation by Vein Color – Similar to the above method, this involves rotating by vein color (e.g. Mon. – Red, Tues. – White, Weds. – Green) By using these methods, one can ensure that the alkaloid profiles are as varied as possible on consecutive days, which can keep tolerance at bay for a much longer period of time. Note: Stem and vein kratom is often used as a substitute to further reduce tolerance, as its alkaloid profile is typically very different than the plain leaf.' However, because using this technique to it’s fullest requires 3-5+ different strains, this method of tolerance reduction, may not fit the means of everyone. There are a variety of other ways to supplement tolerance reduction, including: Magnesium Magnesium supplementation is a great way to keep kratom tolerance low due to its NMDA antagonist effects, which are the primary opiod tolerance regulators. There are many studies supporting this, one of which can be found in April 1998’s publication of Anesthesia & Analgesia. Exercise Exercise is a very effective yet under rated method of reducing tolerance. Exercise’s reduction of tolerance is cumulative, meaning the more you exercise, and the more in shape you are, the less tolerance is developed, which potentiates the medicinal effects of kratom.
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TRADITIONAL DOSAGE Kratom Bible

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TRADITIONAL DOSAGE

Dosage has been a key factor for those looking for specific effects. By dosing too low, the medicinal capabilities are nulled, while dosing too high can often lead to relatively harmless, but potentially unpleasant side-effects, such as the “wobbles” and minor nausea. To learn about kratom dosage, refer below.

Average Dosage by Grams Mild – 1 to 2 grams Moderate – 2-4.5 grams High – 4.5 – 8 gramsAverage Dosage by Teaspoon Mild – .5 to .9 tsp Moderate – 1 to 2 tsp High – 2 to 3.5 tsp

It should be noted that due to varying potency between strains and plants, this estimate is in no way standardized, instead it an estimate based on historical and experiential reports. Doses at the the “high” end of the spectrum are also much more likely to cause side-effects, depending upon the strain.

DOSAGE INTERVAL

STRAIN DIFFERENCES

For best effect, many have found that this plant should not be taken in high doses regularly, as some of the medicinal effects can diminish. However, those who use this plant to combat chronic pain may find this inevitable, as pain doesn’t operate in a convenient time-cycle.

EFFECTS BY DOSAGE

Something that is frequently encountered with a variety of strains is the difference in effects at differing doses. Although this varies depending upon the strain and where you buy kratom, typically, lower doses are relatively more stimulating than higher doses; while the cause of this is not well known, it likely has to do with the sedation curve of 7-hydroxymitragynine. For anyone inexperienced with kratom, it is essential to know about the philosophy, theory and advice regarding kratom dosage.

Differences between strains is a factor that can’t be overlooked when calculating a dosage. There are a few primary strains that should be dosed relatively lower than the average, these strains are: Maeng Da – Potent, active at lower doses Bali – Side effects encountered at lower doses in comparison to other strains Thai – Can be overstimulating for some at higher doses Because of this, it is a good idea to modify dosage with these strains accordingly in order to achieve best results. Some strains, such as Borneo, can be dosed relatively higher, due to their lack of side-effects. Because of this variability in strains, it is advisable to start low with any new or unknown strain.

EMPTY STOMACH

THE “LESS IS MORE” THEORY

The “less is more” theory is very popular among kratom forums, and there is some evidence to back this theory. Almost every strain has an optimal dose for both medicinal and euphoric effects, and dosage above this ideal threshold can have reverse effects due to mu opiod antagonists such as corynantheidine. Now, it’s important to note that different strains have differing levels of this alkaloid, so this statement may not apply to all strains, however, the majority of strains are affected. The “less is more” theory, is also advisable because lower dosage also creates less tolerance to effects, which can increase the plant’s medicinal potential over time.

As plain leaf has to be digested in order to have medicinal benefit, it is considered best taken on an empty stomach, as this will ensure the effects are delivered quickly and properly. Because eating is a necessity, it may not always be possible to use it in this manner; for this reason, many have made kratom tea to deliver effects more quickly.

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EXTRACT GUIDE

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EXTRACT GUIDE

While typically not as well-rounded as the plain leaf in effects, kratom extracts can certainly serve a purpose for those with chronic pain or other debilitating conditions in which the plain leaf will not suffice. There are a large variety of different types of extracts with varying effects, based upon both the method of extraction as well as the base plant material used to make them. Read below to learn about these different extract types.

WATER BASED EXTRACTS

KRATOM RESIN EXTRACTS

Water-based kratom extracts are by far the most common variety. As the name implies, the extract is performed by: dissolving a portion of alkaloids into water, straining the powder, and evaporating the water. This process leaves a brownish, more alkaloid-concentrated version of the plain leaf behind. Water extracts are commonly referred to with an ‘x’ (e.g. 10x, 25x), which implies how much plain leaf material was used to create the same weight of resulting extract. Sadly, these figures are nearly always incorrect due to vendor dishonesty.Pros: More alkaloid-concentrated than plain leaf Can be used in addition to plain leaf to potentiate effects Relatively side-effect free in comparison to resin and full-spectrum extracts More stimulating than the plain-leaf base material Ability to dissolve in water Cons: Typically not very effective unless taken in conjunction with plain leaf Not a well-rounded extract in terms of effects (less pain-killing effect and sedation) High price per potency Can increase tolerance
In comparison to water-based extractions, kratom resin extractions have a much more well-rounded profile of effects. These extracts are typically performed by extracting kratom with both a polar solvent and a non-polar solvent; a simple example of this would be water and ethanol. Like the water extract, the powder is strained and the alkaloid saturated non-polar/polar solvent is left to dry.Pros: Full-spectrum of effects Ease of use Easy storage High potency per weight Cons: More expensive than plain leaf Side-effects to potency ratio comparable to plain leaf Temperature sensitive (melts in minor heat)

ENHANCED LEAF

KRATOM TINCTURES

Unlike the other forms of extracts, kratom tinctures can vary in their method of extraction and their potency; because of this, buying them from an disreputable source can leave one disappointed. On the other hand, when they are done well, they can be quite potent.Pros: Ease of use Fast-acting Convenience of storage Cons: Typically expensive Variable Potency Rarely provide a full-spectrum of effects Rapid development of tolerance

Enhanced leaf has become the go-to choice of many extract users due to it’s high potency and lack of side effects. Enhanced leaf is used by taking a highly potent kratom extract, dissolving it in a solution, soaking kratom leaves/powder in this solution and letting it dry. When done correctly, this method can create a highly potent leaf. One of the most popular enhanced leaf blends of our era is known as UEI (Ultra Enhanced Indo).Pros: Very potent when done well Lack of side-effects per potency Typically well-rounded Highly effective for pain Cons: Rapid development of tolerance Can cause some withdrawal symptoms upon abrupt cessation after prolonged use Relatively high price
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MODERATE STRAINS

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MODERATE STRAINS

Many prefer a moderate strain as their daily go-to, due to its potent, yet smooth, effects. Currently, the most popular moderate strain is Green Malaysian; however, other sub-strains, vein types and breeding can make an overall sedating or stimulating strain moderate.

GREEN MALAYSIAN

Stimulation: 4-6 / 10 Pain Relief: 6 – 8 / 10 Mood: 7 – 8.5 / 10

Green Malaysian has long been known as one of the longest-lasting strains due to leaf cell-wall density. Many remark on this strain’s unique nootropic effects, which, despite heavy stimulation, can increase focus and patience for quite long periods of time. Interestingly, these effects are typically only noticed in retrospect due to its smooth character of effects.

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Kratom Bible STIMULATING STRAINS

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Stimulating strains are some of the most desirable strains for those with fatigue or depression, as well as for those who need to sustain energy and focus for long periods of time.

THAI KRATOM

MAENG DA KRATOM

Thai kratom is well-known for its powerful energetic effects. The unique alkaloid profile of Thai kratom often provokes different reactions between different users, and may not be for everyone. However, this strain has a very dedicated following, unlike anything we have seen with other varieties of kratom. The pain-killing effects of Thai are variable; typically, red vein thai (commonly called RVT) is the most effective in regards to analgesia, whereas white and green vein thai strains, while stimulating and a great kratom strain for depression, are lacking in this area.

Maeng Da has been widely renowned as one of the most potent strains of kratom, and for good reason — it can provide both high levels of pain relief and stimulation. This strain has been ideal for those with pain who don’t want to sacrifice energy levels, as well as those who are looking for a mood-boost.Stimulation: 7 – 8.5 / 10 Pain Relief – 7.5 – 10 / 10 Mood: 7.5 – 10 / 10

Stimulation: 8 to 9.5 / 10 Pain Relief: 4 – 8 / 10 Mood: 6 – 9 / 10

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STRAIN ANALYSIS

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Due to different growth regions and breeding, kratom has evolved into a variety of different strains, which can be very different in effects. There are three primary effect categories one can divide strains into: stimulating, sedating and moderate. It should be noted that every plants within a strain can vary, so in no way are these analyses set in stone, rather they based upon an average of verifiable user reports to provide a guide to the strain as a whole.

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NOOTROPIC (COGNITION ENHANCING) EFFECTS

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Nootropic substances are a relatively new field of interest, yet it shows much promise. Interestingly, due to strain differences, it has been used as a nootropic in several different areas, such as focus and memory. Unlike traditional medications for focus, kratom doesn’t make your focus “stick” psychologically, rather it dampens psychological background noise, promoting natural focus ability. Because strain differences can vary, there is typically no set dose for peak cognition boosting effects — though it typically ranges from low/medium to medium.

Strains Green Malaysian Thai Maeng DaPreferred Vein Color Green White

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IMMUNE SYSTEM STIMULATION

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Isopteropodine Isorhynchophylline Isomitraphylline MitraphyllineKratom can be extremely effective for boosting the immune system for conditions ranging from the common cold to the flu, or even more serious conditions. Because of this, many have learned to take it at the onset of a sickness to dramatically reduce its duration.

Strains Green Malaysian BorneoDosage Moderate

Preferred Vein Color Green

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PSYCHOLOGICAL EFFECTS(ANXIETY, DEPRESSION AND MOOD-LIFTING)

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The psychological effects of kratom are of a very unique nature in comparison to other plants found in nature, contain both sedating and stimulating properties; these effects can differ depending on the strain, plant and one’s own personal chemistry. Nearly any strain can cause general mood-lifting, but the differences in strain can shift the spectrum of effects between stimulating and sedating.

DEPRESSION

Strains Thai Maeng Da Green MalaysianDosage Moderate

Preferred Vein Color White

According to uses, this plant may also be beneficial for the treatment of depression; however, not every strain is fit for this purpose. The more sedating strains may have some temporary effects on depression, but are lacking in effectiveness long term.

ANXIETY RELIEF

There are several ways to maximize anxiety relief through kratom — the ideal strain for anxiety relief is a borneo strain, though other sedating strains can work effectively, and can also double as a great kratom for sleep. A borneo kratom strain has a subtle, yet powerful effect of destroying anxiety and restlessness better than nearly any other strain.

Strains Borneo Bali IndoDosage Moderate

Preferred Vein Color Red

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KRATOM AND OPIATE WITHDRAWAL/ADDICTION

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Because of this plant’s pain-killing and mood-lifting effects, it has been used effectively to quit opiates and dampen withdrawal symptoms for both prescribed pain medication and illegal narcotics. You can find many cases of people using kratom for opiate withdrawal and addiction to both help transition to sobriety, and to combat cravings and post acute withdrawals as a maintenance substance.

Strains Borneo Bali Indo Maeng Da (Situational)Preferred Strain Color RedDosage Moderate/High
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